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CBD and Parkinson´s - CBDNOL
  • CBD and Parkinson´s

    CBD and Parkinson
    For the last 10 years, we've seen an increase in cannabis popularity and use, whether for recreational or medical purposes. An increasing number of researches are being conducted, in particular to test medical claims regarding cannabis and its active chemical compounds. One of these compounds is short cannabidiol or CBD. CBD is considered to be a broad range of potential medical applications; one of these applications is that it helps in Parkinson's disease-related symptoms.

    cannabidiol

    CBD is one of the hundred active cannabinoids found in cannabis, and it accounts for 40% of the plant extract. One of the main reasons why CBD is being explored for medicinal properties is that, unlike the more popular cannabinoid THC, it is not psychoactive. In layman terms, CBD does not get you high, which is ideal for medical treatments since they are preferred to have minimal side effects. Studies suggest that even at high doses CBD is still well tolerated and safe. Some of the medicinal properties for which CBD is valued are the reduction of nausea, the fight against anxiety and depression, the fight against tumor and cancer cells and so on. Unfortunately, most of this evidence comes from animal testing, as there are only a few studies that have been done on humans. In addition, CBD remains illegal in many parts of the world, demonstrating that it is crucial to do more research on CBD and its impact on human health and disease.

    PARKINSON'S DISEASE

    Parkinson's disease is a progressive, degenerative disorder of the central nervous system. It mainly affects motor activity and gets worse over time. Because it is a progressive disease, the symptoms generally come slowly over time. The symptoms can be divided into three groups: primary motor symptoms, secondary motor symptoms and non-motor symptoms. Primary motor symptoms are those that begin early in the illness, such as tremors, stiffness, slowness of movement, and difficulty walking. These primary motor symptoms are collectively referred to as Parkinsonism. As the disease progresses, other symptoms may take place, dementia is one of the most common.

    Parkinson's disease in most people is idiopathic, which means that it has no specific known cause. However, it is believed that the cause includes genetic and environmental factors. Although PD is considered a non-genetic disorder, 15% of people who have PD have a first degree relative that has the same disorder. As far as environmental factors are concerned, there seems to be a link between PD and pesticide exposure, head injuries and life in the country.

    What PD is that it affects the nerve cells (neurons) in a particular part of the brain, called the substantia nigra. Most of these neurons produce dopamine, a chemical that acts as a neurotransmitter in the brain, meaning that it sends signals to other nerve cells. There are five ways in which the brain is connected and through which dopamine is sent, PD affects all of them. As Parkinson's disease progresses, the amount of dopamine produced by the brain decreases so that a person is unable to control their movement (and other functions) normally. Lewy bodies are another major pathological feature of Parkinson's disease, with the exception of nerve cell deterioration. Lewy bodies are abnormal aggregates of proteins that can develop in nerve cells and be the cause of cell death.

    There are currently over 10 million people diagnosed with Parkinson's disease, with men being more affected than women. The average life expectancy after diagnosis is between 7 and 14 years and there is no known cure for the disease. But there are various medications, surgery and other methods that can provide relief from the symptoms. One of these methods could be CBD.
    CBD AND PARKINSON'S DISEASE

    A recent study, conducted by a team of researchers from Brazil, showed that daily treatment with cannabidiol improved the well-being and quality of life of patients diagnosed with Parkinson's disease. Twenty-one patients were administered CBD in gelatin capsules over a period of 6 weeks. Three doses were administered: 300 mg per day, 75 mg per day, and one placebo. Patients who improved the most were those who received the 300mg dose. However, it should be noted that the treatment did not affect the disease, only the symptoms, and the small size of the patient group may have limited the results. On the other hand, animal studies indicate that cannabis compounds may slow the progression of PD and other neurodegenerative conditions.

    It is safe to say that CBD and other chemical compounds found in cannabis, as various studies have concluded, can alleviate a number of health problems, conditions and shortcomings. Still, there is much more work to do in terms of research on CBD and the impact on human health. Parkinson's disease, unfortunately, serves as a reminder why this issue, as said, is of great importance to public health care. We hope that in the world of tomorrow, the human race will use all of its natural resources available to everyone to fight problems and diseases in some way.
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